Author

Jennifer G. Goldman

Northwestern UniversityORCID 0000-0001-5014-7535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alessandro SetteiD· 3 shared Antoine FreuchetiD· 3 shared April FrazieriD· 3 shared Cecilia S. Lindestam ArlehamniD· 3 shared David L. SulzeriD· 3 shared Irene LitvaniD· 3 shared Roy N. AlcalayiD· 3 shared Emil JohanssoniD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Alessandro SetteORCID

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3 papers

Recent·Most cited

T cell responses towards PINK1 and α-synuclein are elevated in prodromal Parkinson's disease

Emil Johansson, Antoine Freuchet, Gregory P. Williams, Tanner Michealis, April Frazier, Irene Litvan, Jennifer G. Goldman, Roy N. Alcalay, David G. Standaert, Amy W. Amara, Natividad P. Stover, Edward A. Fon, Ronald B. Postuma, John Sidney, David L. Sulzer, , Alessandro Sette

The paper examines T cell responses to PINK1 and α-synuclein in prodromal Parkinson's disease, finding elevated reactivity comparable to clinically diagnosed PD.

npj Parkinson s Disease · May 26, 2025Peer-reviewedNeuroscience

Differential memory enrichment of cytotoxic CD4 T cells in Parkinson's disease patients reactive to α-synuclein

Antoine Freuchet, Emil Johansson, April Frazier, Irene Litvan, Jennifer G. Goldman, Roy N. Alcalay, David L. Sulzer, Cecilia S. Lindestam Arlehamn, Alessandro Sette

The paper investigates T cell subsets in Parkinson's disease patients reactive to α-synuclein, finding reduced Granulysin+ CD4 cytotoxic TEM cells and altered CELSR2 expression.

npj Parkinson s Disease · May 14, 2025Peer-reviewedNeuroscience

PINK1 is a target of T cell responses in Parkinson's disease

Gregory P. Williams, Antoine Freuchet, Tanner Michaelis, April Frazier, Ngan K. Tran, João Rodrigues Lima-Júnior, Elizabeth Jane Phillips, Simon Alexander Mallal, Irene Litvan, Jennifer G. Goldman, Roy N. Alcalay, John Sidney, David Sulzer, Alessandro Sette, Cecilia S. Lindestam Arlehamn

The paper identifies PINK1 as an autoantigen targeted by T cells in Parkinson's disease, with reactivity predominantly observed in male patients.

Journal of Clinical Investigation · Dec 17, 2024Peer-reviewedImmunology