Author
Hospital for Sick Children
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Terence Gall-Duncan, Sangyoon Y. Ko, Isabelle K. Quick…·Christopher E. Pearson
This study shows that reducing somatic CAG expansions in HD mice improves motor function and disease markers, suggesting therapeutic potential for HD and similar repeat expansion diseases.
Mila Mirceta, Monika H.M. Schmidt, Natalie Shum…·Christopher E. Pearson
This paper shows C9orf72 expansions create a folate-sensitive fragile site FRA9A, leading to chromosomal instability and immune responses in patient cells and mice.
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic…·Christopher E. Pearson
The paper investigates the roles of canonical and alternative RPA in CAG repeat diseases, finding that Alt-RPA antagonizes RPA's suppression of CAG expansions, contributing to disease pathogenesis.