APOE Protects Against Severe Infection with Mycobacterium tuberculosis by Restraining Production of Neutrophil Extracellular Traps
Dong Liu, Dat Mai, Ana N. Jahn, Tara A. Murray, John D. Aitchison, Benjamin Henry Gern, Kevin B. Urdahl, Alan A. Aderem, Alan H. Diercks, Elizabeth S. Gold
This study shows that APOE protects against severe tuberculosis by limiting neutrophil extracellular trap formation, which exacerbates infection in Apoe-/- mice.
PLoS Pathogens · Jun 16, 2025Peer-reviewedImmunology