Benjamin Henry Gern

This study shows that ferroptosis, a form of cell death, is enhanced by a virulent Mtb strain, SA161, and inhibiting it reduces bacterial spread in mice.

This study uses single-cell RNA sequencing to identify immune dynamics distinguishing protection from susceptibility to tuberculosis in mice.

This study shows that prior immunity influences tuberculosis lesion structure by modulating neutrophil and T cell responses, leading to different pathological outcomes.

This study shows that APOE protects against severe tuberculosis by limiting neutrophil extracellular trap formation, which exacerbates infection in Apoe-/- mice.

This study shows T cell-derived IFN-gamma is critical for controlling Mycobacterium tuberculosis in the murine lung, despite equivalent bacterial burdens in T cell-deficient mice.