Author

Taryn J. Polanco

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ashish JainiD· 1 shared Davide CacchiarelliiD· 1 shared Delaney Wood· 1 shared Dosh WhyeiD· 1 shared Elizabeth D. ButtermoreiD· 1 shared Gayathri Rajaram SrinivasaniD· 1 shared Heather E. OlsoniD· 1 shared Kathleen E. DonovaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Ashish JainORCID

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1 paper

Recent·Most cited

Excitatory Cortical Neurons from CDKL5 Deficiency Disorder Patient-Derived Organoids Show Early Hyperexcitability Not Identified in Neurogenin2 Induced Neurons

Madison R. Glass, Dosh Whye, Nickesha Camille Anderson, Delaney Wood, Nina R. Makhortova, Taryn J. Polanco, Kristina H. Kim, Kathleen E. Donovan, Gayathri Rajaram Srinivasan, Lorenzo Vaccaro, Ashish Jain, Davide Cacchiarelli, Liang Sun, Heather E. Olson, Elizabeth D. Buttermore, Mustafa Şahin

This study compares neuronal activity and gene expression in CDD patient-derived neurons from two differentiation methods, finding early hyperexcitability in organoid-derived neurons but not induced neurons.

Neurobiology of Disease · Sep 8, 2025Peer-reviewedNeuroscience