A shared transcriptional network in the nucleus accumbens supports resilience to chronic stress across sex.
Trevonn M. Gyles, Leanne Melissa Holt, Lyonna F. Parise, Rachel L. Fisher-Foye, Arthur Godino, Caleb J. Browne, Brian T. Kipp, Angelica M. Minier-Toribio, Tamara Markovic, Teagan Daly, Romain Durand-de Cuttoli, Long Li, Aarthi Ramakrishnan, Molly S. Estill, Matthew T. Rivera, , Eric J. Nestler
The paper identifies a shared transcriptional network in the nucleus accumbens that supports stress resilience in both sexes and shows causal effects of hub genes.
bioRxiv · Feb 18, 2026 · PreprintNeuroscience