Author

Tegvir S Boora

McGill University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Approach:mixed model· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Stéphane A. LaporteiD· 2 shared Aaron Cho· 1 shared Andréi S. RodiniD· 1 shared Eric Barbeau· 1 shared Franziska M. HeydenreichiD· 1 shared Hanyu CheniD· 1 shared Jay Y. Paranjpe· 1 shared Madalina Macovei· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

Stéphane A. LaporteORCID

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2 papers

Recent·Most cited

Allosteric pathways govern Gα protein coupling selectivity at promiscuous GPCRs

Tegvir S Boora, Hanyu Chen, Aaron Cho, Wijnand J. C. van der Velden, Yoon Namkung, Yubo Cao, Jay Y. Paranjpe, Franziska M. Heydenreich, Andréi S. Rodin, Sergio Branciamore, Nagarajan Vaidehi, Stéphane A. Laporte

The paper identifies allosteric pathways that determine G protein coupling selectivity in promiscuous GPCRs using a combination of mutagenesis, simulations, and machine learning.

bioRxiv · Sep 3, 2026 · PreprintPharmacology & Toxicology

Optimization of the prostaglandin F2α receptor for structural biology

Marine Salze, Sébastien Chrétien, Tegvir S Boora, Madalina Macovei, Eric Barbeau, Véronique Blais, Stéphane A. Laporte, Martin Audet

This paper optimizes the prostaglandin F2α receptor (FP) for structural biology by improving its purification yield and in vitro stability through protein engineering.

PLoS ONE · Jul 18, 2025Peer-reviewedPharmacology & Toxicology