Author
Institute for Research in Immunology and CancerORCID 0000-0002-8049-4383Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Tegvir S Boora, Hanyu Chen, Aaron Cho…·Stéphane A. Laporte
The paper identifies allosteric pathways that determine G protein coupling selectivity in promiscuous GPCRs using a combination of mutagenesis, simulations, and machine learning.
Adrián Morales-Pastor, Tamara Miljuš, Miguel Dieguez-Eceolaza…·Jana Selent
The paper investigates how multiple triggers on an allosteric communication network influence preferential coupling of the CB2R to Gi2 over β-arrestin1, revealing insights into GPCR signaling mechanisms.
Eline J. Koers, Bradley Angus Morgan, Franziska M. Heydenreich…·Dmitry B. Veprintsev
The paper shows that cell-to-cell variations in V2R subcellular localization are independent of expression levels and influenced by cell-specific environments.
Christopher DeBoever, AJ Venkatakrishnan, Joseph M. Paggi…·Manuel A. Rivas
The paper identifies 138 associations between common protein-altering variants in GPCR genes and various phenotypes using UK Biobank data.
Adam Gosztolai, Jörg Schumacher, Volker Behrends…·Mauricio Barahona
The paper investigates how GlnK and GlnB regulate glutamine synthetase activity in E. coli during nitrogen starvation and upshift using experiments and a biochemical model.