Teresa M Przytycka

The paper investigates how gene copy number, dosage compensation, and expression noise interact in Drosophila, finding that one dose genes show higher expression variability and that dosage compensation increases noise in autosomal genes but not X-linked genes.

The paper examines gene dosage effects in Drosophila deficiency heterozygotes, finding varied transcriptional responses and minimal long-range regulatory impacts from breakpoints.