Author

Kevin Cook

Amgen (United States)Primary ORCID profile (0009-0002-5686-6674 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Kevin CookiD1 paper

Biology Disciplines

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Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alekhya ParvathaneniiD· 1 shared Andrea L. BredemeyeriD· 1 shared Andrew L. KoenigiD· 1 shared Attila Kovacs· 1 shared Blake Jardin· 1 shared Brandon L. Ason· 1 shared Brian OliveriD· 1 shared Cale WhitworthiD· 1 shared

Activity by Year

2015-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Alekhya ParvathaneniORCID

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2 papers

Recent·Most cited

Collateral Immune Cell Signaling Compromises the Efficacy of T-cell Engaging Therapies for Cardiac Fibrosis

Steven Hoseong Yang, Alekhya Parvathaneni, Yun-Ling Pai, Andrew L. Koenig, Farid F. Kadyrov, Macee C. Owen, Junedh Amrute, Andrea L. Bredemeyer, Yu-Sung Hsu, Attila Kovacs, Carla J. Weinheimer, Jessica M. Nigro, Lance Yeh, Thomas Williamson, Blake Jardin, , Kory J. Lavine

This study shows that FAP-targeted BiTE(R) molecules, intended to reduce cardiac fibrosis, instead worsen heart function by triggering harmful immune responses.

bioRxiv · Sep 21, 2026 · PreprintImmunology

Genome-wide expression profiling Drosophila melanogaster deficiency heterozygotes reveals diverse genomic responses.

Hangnoh Lee, Dong-Yeon Cho, Cale Whitworth, Robert Eisman, Melissa Phelps, John Roote, Thomas Kaufman, Kevin Cook, Steven Russell, Teresa M Przytycka, Brian Oliver

The paper examines gene dosage effects in Drosophila deficiency heterozygotes, finding varied transcriptional responses and minimal long-range regulatory impacts from breakpoints.

bioRxiv · Nov 26, 2015Genetics