Brian Oliver

A mdg4 Retrotransposon Screen for X-linked Female Sterile Alleles and its Relationship with the Transcription Factor OVO

The paper screens for X-linked female sterile alleles using mdg4 retrotransposon insertions and finds that while mdg4 preferentially inserts near OVO binding sites, only a subset of sterile alleles result from this mechanism.

Cell type specific allometry controls sex-differences in Drosophila body size

The paper identifies sex-specific allometric strategies in Drosophila organs, showing how cell size and number differ between sexes to drive body size differences.

Conserved Molecular Responses to Arsenite Exposure in Drosophila melanogaster

This study identifies conserved molecular responses to arsenite exposure in Drosophila, revealing shared pathways with human arsenic-related diseases.

Female germline expression of OVO transcription factor bridges Drosophila generations

The paper investigates OVO's role in Drosophila female germline development, showing its continuous expression across generations and essential function in germ cell viability.

Diverse somatic Transformer and sex chromosome karyotype pathways regulate gene expression in Drosophila gonad development

The paper investigates how somatic Transformer and sex chromosome karyotype pathways regulate gene expression during Drosophila gonad development, showing their combined and exclusive effects on germ cell development.

OVO Positively Regulates Essential Maternal Pathways by Binding Near the Transcriptional Start Sites in the Drosophila Female Germline

The paper identifies OVO as a master transcriptional regulator in Drosophila female germline development by showing it binds near TSSs of essential maternal genes and regulates their expression.

Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes

The paper provides single nucleus and single cell RNA-seq data from Drosophila testes to study spermatogenesis, identifying rare cell types and developmental transitions.

Fly Cell Atlas: a single-cell transcriptomic atlas of the adult fruit fly

The paper creates a single-cell transcriptomic atlas of the adult fruit fly, identifying over 250 cell types and analyzing gene signatures and sexual dimorphism across tissues.

Dynamic Sex Chromosome Expression in Drosophila Male Germ Cells

The paper shows that X and 4th chromosomes are inactivated while Y chromosomes are active in Drosophila primary spermatocytes using single-cell RNA-Seq.

IRBIT Directs Differentiation of Intestinal Stem Cell Progeny to Maintain Tissue Homeostasis

This study shows that IRBIT suppresses RNR activity in intestinal stem cell progeny to drive differentiation into enterocytes, maintaining gut tissue integrity in Drosophila.

Reconstruction of Gene Regulatory Networks by integrating biological model and a recommendation system

The paper introduces NetREX-CF, a method combining collaborative filtering and sparse network component analysis to reconstruct gene regulatory networks, outperforming existing methods.

Reannotation of eight Drosophila genomes

The paper reannotates eight Drosophila genomes using a transcriptome assembly approach trained on Drosophila melanogaster, adding tens of thousands of new gene models and orthologs.

Non-canonical Drosophila X chromosome dosage compensation and repressive topologically-associated domains

The paper investigates non-canonical dosage compensation on the Drosophila X chromosome, showing that repressive chromatin domains contribute to gene expression balance in males.

The High-throughput WAFFL System for Treating and Monitoring Individual Drosophila melanogaster Adults

The paper introduces a high-throughput system for feeding, monitoring, and assaying Drosophila melanogaster adults using 96-well consumables.

Drosophila small ovary encodes a zinc-finger repressor required for ovarian differentiation

This study identifies the small ovary (sov) gene in Drosophila, which encodes a zinc-finger protein required for ovarian differentiation by repressing cell signaling and transposons.

NetREX: Network Rewiring using EXpression - Towards Context Specific Regulatory Networks

NetREX constructs context-specific regulatory networks by integrating expression data and context-agnostic networks, showing improved biological consistency in Drosophila data.

Interplay between copy number, dosage compensation and expression noise in Drosophila

The paper investigates how gene copy number, dosage compensation, and expression noise interact in Drosophila, finding that one dose genes show higher expression variability and that dosage compensation increases noise in autosomal genes but not X-linked genes.

Genome-wide expression profiling Drosophila melanogaster deficiency heterozygotes reveals diverse genomic responses.

The paper examines gene dosage effects in Drosophila deficiency heterozygotes, finding varied transcriptional responses and minimal long-range regulatory impacts from breakpoints.