Tax1bp1 enhances bacterial virulence and promotes inflammatory responses during Mycobacterium tuberculosis infection of alveolar macrophages
Jeffrey Chin, Nalin Abeydeera, Teresa Repasy, Rafael Rivera‐Lugo, Gabriel Mitchell, Vinh Q Nguyen, Weihao Zheng, Alicia Richards, Erica J. Stevenson, Danielle L. Swaney, Nevan J. Krogan, J. Ernst, Jeffery S. Cox, Jonathan M. Budzik
This study shows Tax1bp1 promotes Mtb growth in alveolar macrophages and enhances inflammatory responses, while restricting Mtb in bone marrow-derived macrophages.
PLoS Pathogens · Oct 31, 2025Peer-reviewedMicrobiology