Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology
Arthur Wickenhagen, Meaghan Flagg, Julia Rebecca Port, Claude Kwe Yinda, Kerry Goldin, Shane Gallogly, Jonathan E. Schulz, Tessa R. Lutterman, Brandi N. Williamson, Franziska Karola Kaiser, Reshma Koolaparambil Mukesh, Sarah van Tol, Brian J. Smith, Neeltje van Doremalen, Colin A. Russell, , Vincent Jacobus Munster
This study evaluates the fitness and pathogenesis of Omicron variants in the upper and lower respiratory tracts, finding increased URT fitness with reduced lung pathology.
Nature Communications · Jan 11, 2025Peer-reviewedMicrobiology