Author

Théo Guez

École Nationale Supérieure de Chimie de Montpellier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:snRNA-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Ben R HawleyiD· 2 shared Françoise DebartiD· 2 shared Jean‐Jacques VasseuriD· 2 shared Samie R. JaffreyiD· 2 shared Andrea RentmeisteriD· 1 shared Diana Toczydłowska-Socha· 1 shared Eric Lieberman GreeriD· 1 shared Hani GoodarziiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMolecular Biology

Ben R HawleyORCID

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2 papers

Recent·Most cited

Identification of the m6Am methyltransferase PCIF1 reveals the location and functions of m6Am in the transcriptome

Konstantinos Boulias, Diana Toczydłowska-Socha, Ben R Hawley, Noa Liberman, Ken Takashima, Sara Zaccara, Théo Guez, Jean‐Jacques Vasseur, Françoise Debart, Lakshminarayanan Aravind, Samie R. Jaffrey, Eric Lieberman Greer

The paper identifies PCIF1 as the m6Am methyltransferase and develops a method to accurately map m6Am sites, revealing its role in mRNA stability.

Molecular Cell · Jul 3, 2019Peer-reviewedMolecular Biology

The RNA demethylase FTO targets m6Am in snRNA to establish distinct methyl isoforms that influence splicing

Jan Mauer, Miriam Sindelar, Vladimir Despic, Théo Guez, Ben R Hawley, Jean‐Jacques Vasseur, Andrea Rentmeister, Steven S. Gross, Livio Pellizzoni, Françoise Debart, Hani Goodarzi, Samie R. Jaffrey

This study shows FTO demethylates m2-snRNA to regulate splicing by controlling reversible methylation of snRNAs.

Nature Chemical Biology · Feb 18, 2019Peer-reviewedMolecular Biology