Cell BiologybioRxivPreprint
E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled family members
Jeroen M. Bugter, Peter van Kerkhof, Eline Janssen…·Madelon M. Maurice
This study shows RNF43 and ZNRF3 differentially regulate endocytosis of specific Frizzled family members through their transmembrane domains, linking these differences to cancer mutation patterns.
DOI 10.1101/2023.11.23.568206