Author
University Medical Center UtrechtORCID 0000-0001-7865-2816Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Anton Jan Venhuizen, Yvanka van Os, Milo L. Kaptein…·Madelon M. Maurice
This study shows that AXIN1 mutations in HCC lead to reduced Wnt/β-catenin activity and increased YAP/TAZ signaling, enabling niche-independent growth.
Andrea Rodríguez-Alonso, Lía Jove, Gloria Alfonsín…·Angélica Figueroa
This study shows that Hakai promotes colorectal cancer stem cell traits by enhancing Wnt/beta-catenin signaling through LRP4 degradation and that Hakin-1 inhibits these effects.
Gabriele Colozza, Ingrid Jordens, Eric Sosa…·Bon‐Kyoung Koo
This study identifies WNK kinases as regulators of RNF43, showing they control RNF43 membrane levels and WNT signaling, with implications for cancer therapy.
Julian R. Buissant des Amorie, Max A. Betjes, Jochem H. Bernink…·Hugo J.G. Snippert
The paper identifies sequential transcriptomic states of tuft cells along the intestinal crypt-villus axis and shows cytokine-specific differentiation into distinct tuft cell phenotypes.