EGFR/TBK1-dependent mitochondrial quality control contributes to acquired resistance to temozolomide
Lisenn Lalier-Bretaudeau, François Guillonneau, Abed-El-Razzak Saleh, Thomas Cabioch, Alice Boissard, Cécile Henry, Sophie Barillé‐Nion, Judith Raimbourg, Philippe Paul Juin
The paper identifies an EGFR/TBK1-dependent mitochondrial quality control mechanism that contributes to acquired resistance to temozolomide in glioma cells.
bioRxiv · Dec 21, 2025 · PreprintCancer Biology