Alice Boissard

Desmin p.R406W mutation is associated with arrhythmias through structural and electrophysiological remodeling

This study investigates the pathogenic effects of the DES p.R406W mutation, showing it causes electrical and structural heart remodeling linked to arrhythmias and sudden cardiac death.

The Kinase CK1α coordinates Initiation and Termination of the cGAS-STING Pathway

This study identifies CK1 as a bimodal regulator of the cGAS-STING pathway, showing it both promotes DNA sensing and facilitates signaling termination, with therapeutic implications for cancer.

EGFR/TBK1-dependent mitochondrial quality control contributes to acquired resistance to temozolomide

The paper identifies an EGFR/TBK1-dependent mitochondrial quality control mechanism that contributes to acquired resistance to temozolomide in glioma cells.

Tunneling nanotubes propagate preneoplastic cues in a BMP-dependent manner.

The paper shows that tunneling nanotubes (TNTs) transfer preneoplastic signals via BMP-dependent pathways in breast cells, promoting transformation in non-transformed cells.