Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer's disease
Alberto Serrano‐Pozo, Zhaozhi Li, Maya E. Woodbury, Clara Muñoz‐Castro, Astrid Wachter, Rojashree Jayakumar, Annie G. Bryant, Ayush Noori, Lindsay A. Welikovitch, Miwei Hu, Karen Zhao, Fan Liao, Gen Lin, Timothy Pastika, Joseph A. Tamm, , Sudeshna Das
This study uses single-nucleus RNA-sequencing to analyze astrocyte transcriptomic changes across the spatiotemporal progression of Alzheimer's disease, revealing gene expression trajectories and heterogeneity.
bioRxiv · Dec 3, 2022 · PreprintNeuroscience