Author

Joseph A. Tamm

AbbVie (United States)ORCID 0000-0002-7977-2809Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Aicha Abdourahman· 3 shared Alberto Serrano‐PozoiD· 3 shared Bradley T. HymaniD· 3 shared Maya E. WoodburyiD· 3 shared Robert V. TalanianiD· 3 shared Sudeshna DasiD· 3 shared Astrid WachteriD· 2 shared Ayush NooriiD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Aicha Abdourahman

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Author profile →

3 papers

Recent·Most cited

Cerebrovascular Single-Nucleus RNA-Seq Reveals Heat Shock Activation and Vascular Remodeling in Alzheimer's Disease and Primary Tauopathies

L. Daniel Estrella, Swarnali Dasgupta, Akhila Gundavelli, Huan Li, Stanley Yang, Sarah E. Chancellor, Tim Pastika, Aicha Abdourahman, Joseph A. Tamm, Kiran Yanamandra, Nandani Romanul, Fan Liao, Karen Zhao, Gen Lin, Pooja Srinivasa, , Rachel E. Bennett

The paper uses single-nucleus RNA-seq to analyze cerebrovascular transcriptomic changes in Alzheimer's Disease and primary tauopathies, identifying shared heat-shock responses and disease-specific vascular remodeling.

bioRxiv · Jun 28, 2026 · PreprintNeuroscience

Distinct Transcriptomic Responses to A beta plaques, Neurofibrillary Tangles, and APOE in Alzheimer's Disease

Sudeshna Das, Zhaozhi Li, Astrid Wachter, Srinija Alla, Ayush Noori, Aicha Abdourahman, Joseph A. Tamm, Maya E. Woodbury, Robert V. Talanian, Knut Biber, Eric H. Karran, Bradley T. Hyman, Alberto Serrano‐Pozo

The paper examines transcriptomic changes in Alzheimer's disease brain regions associated with Aβ plaques, tangles, and APOE ε4, finding distinct gene expression patterns linked to neuroinflammation and neuronal dysfunction.

Alzheimer s & Dementia · Jul 17, 2023Peer-reviewedNeuroscience

Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer's disease

Alberto Serrano‐Pozo, Zhaozhi Li, Maya E. Woodbury, Clara Muñoz‐Castro, Astrid Wachter, Rojashree Jayakumar, Annie G. Bryant, Ayush Noori, Lindsay A. Welikovitch, Miwei Hu, Karen Zhao, Fan Liao, Gen Lin, Timothy Pastika, Joseph A. Tamm, , Sudeshna Das

This study uses single-nucleus RNA-sequencing to analyze astrocyte transcriptomic changes across the spatiotemporal progression of Alzheimer's disease, revealing gene expression trajectories and heterogeneity.

bioRxiv · Dec 3, 2022 · PreprintNeuroscience