Molecular dissection of protein complexes isolated from sections of human brain
Tarick J. El‐Baba, Corinne A. Lutomski, Jack L. Bennett, Sophie A. S. Lawrence, Sean Anthony Burnap, Frances I Butroid, Olivia B. Ramsay, Titas Radzevicius, Di Wu, Haigang Song, Kenny L. Chan, Lyonna F. Parise, Eric M. Parise, Weston B. Struwe, James W. Murrough, , Carol V. Robinson
The paper develops a method to study endogenous protein complexes in brain tissue and finds mGluR2/3 heterodimers are abundant in specific human brain regions and associated with depression.
bioRxiv · Apr 12, 2026 · PreprintBiochemistry