Author

Sophie A. S. Lawrence

University of OxfordORCID 0009-0005-6652-4792Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Carol V. RobinsoniD· 2 shared Corinne A. LutomskiiD· 2 shared Frances I Butroid· 2 shared Haigang SongiD· 2 shared Tarick J. El‐BabaiD· 2 shared Carla KirschbaumiD· 1 shared Christopher Mullen· 1 shared Di WuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiophysics

Carol V. RobinsonORCID

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2 papers

Recent·Most cited

Defining state-selective lipid binding to brain GPCRs - introducing REVEAL

Sophie A. S. Lawrence, Carla Kirschbaum, Corinne A. Lutomski, Haigang Song, Joshua D. Hinkle, Frances I Butroid, Rafael Donadelli Melani, John E. P. Syka, Christopher Mullen, Tarick J. El‐Baba, Carol V. Robinson

The paper introduces REVEAL, a mass spectrometry method to identify receptor-specific lipid binding in mammalian membrane proteins, showing agonism alters lipid occupancy and plasmalogen lipids are depleted under oxidative stress.

bioRxiv · May 5, 2026 · PreprintBiophysics

Molecular dissection of protein complexes isolated from sections of human brain

Tarick J. El‐Baba, Corinne A. Lutomski, Jack L. Bennett, Sophie A. S. Lawrence, Sean Anthony Burnap, Frances I Butroid, Olivia B. Ramsay, Titas Radzevicius, Di Wu, Haigang Song, Kenny L. Chan, Lyonna F. Parise, Eric M. Parise, Weston B. Struwe, James W. Murrough, , Carol V. Robinson

The paper develops a method to study endogenous protein complexes in brain tissue and finds mGluR2/3 heterodimers are abundant in specific human brain regions and associated with depression.

bioRxiv · Apr 12, 2026 · PreprintBiochemistry