Microbiota-dependent histone butyrylation in the mammalian intestine
Leah A. Gates, Bernardo Sgarbi Reis, Peder J. Lund, Matthew Robert Paul, Marylène Leboeuf, Zara Nadeem, Tom S. Carroll, Benjamin A. Garcia, Daniel Mucida, C. David Allis
The paper shows that histone butyrylation in intestinal epithelial cells is regulated by microbiota and the metabolite tributyrin, and is linked to gene expression.
bioRxiv · Sep 29, 2022 · PreprintMolecular Biology