C. David Allis

This study shows that H3K27me3 maintenance in mature neurons via EZH1 has minimal impact on gene expression and chromatin accessibility.

This study investigates how the conserved SBD of EZH2 regulates PRC2 activity, showing its necessity for histone methylation and cancer cell proliferation.

This study shows that H4K91 mutants alter chromatin occupancy and misregulate neuronal differentiation, leading to microcephaly-like phenotypes in mice.

This study identifies PAF1 and FACT as essential for enhancer activity in MLL-AF4-driven leukemia by maintaining histone acetylation and enhancer-promoter interactions.

The paper shows that histone bivalency regulates the timing of cerebellar granule cell development by controlling gene expression during migration and differentiation.

The paper shows that histone butyrylation in intestinal epithelial cells is regulated by microbiota and the metabolite tributyrin, and is linked to gene expression.

The paper shows that adding lipid-rich albumin to 2i media maintains genomic stability and developmental potency of murine pluripotent stem cells over long-term culture.

The paper shows that histone H2B ubiquitylation regulates histone gene expression in fission yeast by affecting transcription elongation and cell cycle progression.