Author

Tram T N Nguyen

The University of Texas at San Antonio Health Science Center

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Genetics· 1

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Approach:experimental assay· 1

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Gargi GhosaliD· 1 shared Justin W. C. LeungiD· 1 shared Kevin D. RaneyiD· 1 shared Kirk L. WestiD· 1 shared Kyle Tengler· 1 shared Natasha F. KreilingiD· 1 shared

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1 paper

Recent·Most cited

GeneticsNucleic Acids ResearchPeer-reviewedDec 13, 2024

Autophosphorylation of the Tousled-like kinases TLK1 and TLK2 regulates recruitment to damaged chromatin via PCNA interaction

Kirk L. West, Tram T N Nguyen, Kyle Tengler…·Justin W. C. Leung

This study shows that TLK1 and TLK2 hyper-autophosphorylation suppresses their recruitment to damaged chromatin by masking the PIP-box, which is required for PCNA interaction.

2 citations

experimental assay

𝕏 PostBluesky