Justin W. C. Leung

This study shows that LC8 bridges 53BP1 trimers to enhance 53BP1 foci formation, which is critical for DNA repair.

This study shows that TLK1 and TLK2 hyper-autophosphorylation suppresses their recruitment to damaged chromatin by masking the PIP-box, which is required for PCNA interaction.

This study identifies APE2 nuclease as a critical factor for MMEJ repair, showing its role in telomere fusion and DNA repair reporter assays.

This study shows that Sae2/CtIP prevents R-loop accumulation by facilitating their removal, with CtIP nuclease activity playing a critical role in this process.