Author

Truelian Yu

Massachusetts General Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Cammie F. LesseriD· 1 shared Jonathan N. PrunedaiD· 1 shared Kyungsub KimiD· 1 shared Lisa GoersiD· 1 shared Marcos Antonio Valdespino DiaziD· 1 shared Michele E. MuscoloiD· 1 shared Rowan KarriD· 1 shared Tera C. LeviniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMicrobiology

Cammie F. LesserORCID

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1 paper

Recent·Most cited

Differential targeting of human pyroptotic Caspase-5 and Caspase-4 by Shigella OspC2 and OspC3

Kyungsub Kim, Marcos Antonio Valdespino Diaz, Rowan Karr, Michele E. Muscolo, Lisa Goers, Truelian Yu, Tera C. Levin, Jonathan N. Pruneda, Cammie F. Lesser

This paper identifies OspC2 and OspC3 as Shigella effectors that specifically target Caspase-5 and Caspase-4, respectively, through their PCS domains, revealing evolutionary adaptations in host and pathogen interactions.

mBio · Feb 18, 2026Peer-reviewedMicrobiology