Author

Rowan Karr

Massachusetts General HospitalORCID 0009-0008-9923-286XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Cammie F. LesseriD· 1 shared Jonathan N. PrunedaiD· 1 shared Kyungsub KimiD· 1 shared Lisa GoersiD· 1 shared Marcos Antonio Valdespino DiaziD· 1 shared Michele E. MuscoloiD· 1 shared Tera C. LeviniD· 1 shared Truelian Yu· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMicrobiology

Cammie F. LesserORCID

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1 paper

Recent·Most cited

MicrobiologymBioPeer-reviewedFeb 18, 2026

Differential targeting of human pyroptotic Caspase-5 and Caspase-4 by Shigella OspC2 and OspC3

Kyungsub Kim, Marcos Antonio Valdespino Diaz, Rowan Karr…·Cammie F. Lesser

This paper identifies OspC2 and OspC3 as Shigella effectors that specifically target Caspase-5 and Caspase-4, respectively, through their PCS domains, revealing evolutionary adaptations in host and pathogen interactions.

2 citations

humanexperimental assay

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