U. Vogel

Particulate matter constituents trigger the formation of extracellular amyloid beta and Tau-containing plaques and neurite shortening in vitro

This study shows that particulate matter exposure in vitro causes amyloid beta plaques and neurite shortening in neuron-like cells, resembling Alzheimer's disease features.

Cell circuits underlying nanomaterial specific respiratory toxicology

This study uses single-cell RNA-sequencing to analyze how different nanomaterials affect lung inflammation in mice, identifying cell type-specific responses and mechanisms.

Binucleated cell formation and oncogene expression after particulate matter exposure is preceded by microtubule disruption, dysregulated cell cycle, prolonged mitosis, and septin binding

This study shows that TiO2 nanotubes and MWCNTs induce different cancer-related changes in vitro, with TiO2 nanotubes disrupting microtubules and inducing binucleated cells, while MWCNTs activate the STING pathway.