PhysiologybioRxiv
Spatiotemporal EP4-fibulin-1 expression is associated with vascular intimal hyperplasia
S. Okumura, U. Yokoyama, S. Oka…·Y. Kato
This study identifies EP4 and fibulin-1 as key regulators of vascular intimal hyperplasia through VSMC proliferation, suggesting EP4 antagonists or fibulin-1 downregulation as potential therapeutic strategies.
DOI 10.1093/cvr/cvae211