Zinc-binding motif acts as an oxidative stress sensor to regulate TRPM7 channel activity
H. Inoue, T. Murayama, T. Kobayashi, M. Konishi, U. Yokoyama
This study identifies the zinc-binding motif in TRPM7 as critical for oxidative stress sensing and Mg2+-dependent regulation of channel activity.
bioRxiv · Sep 28, 2020Physiology