Author

Uma Vrudhula

Cold Spring Harbor Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:electronic health records· 1

Frequent Co-Authors

Lucas CheadleiD· 4 shared Austin FerroiD· 3 shared Yohan S. S. AugusteiD· 2 shared Adrian Berisha· 1 shared Adrian M. GomeziD· 1 shared Anne-Sarah Nichitiu· 1 shared Anosha Arshad· 1 shared Deepanjali DwivediiD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersNeuroscience

Lucas CheadleORCID

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4 papers

Recent·Most cited

Disruption of Cholinergic Retinal Waves Alters Visual Cortex Development and Function

Timothy J. Burbridge, Jacob M Ratliff, Deepanjali Dwivedi, Uma Vrudhula, Francisco Alvarado-Huerta, Lucas Sjulson, Leena Ali Ibrahim, Lucas Cheadle, Gord Fishell, Renata Batista‐Brito

This study disrupts cholinergic retinal waves in mice and shows impaired visual cortex development and function, including altered retinotopy and sensory processing.

bioRxiv · Apr 5, 2024 · PreprintNeuroscience

The cytokine receptor Fn14 is a molecular brake on neuronal activity that mediates circadian function in vivo

Austin Ferro, Anosha Arshad, Leah Boyd, Tess Stanley, Adrian Berisha, Uma Vrudhula, Adrian M. Gomez, Jeremy C. Borniger, Lucas Cheadle

This study shows that Fn14, a cytokine receptor, acts as a molecular brake on neuronal activity in adult mice, influencing circadian rhythms, sleep, and memory.

bioRxiv · Apr 2, 2024 · PreprintNeuroscience

Oligodendrocyte precursor cells engulf synaptic inputs in an experience- and microglia-dependent manner

Yohan S. S. Auguste, Austin Ferro, Jessica R. Dixon, Uma Vrudhula, Jessica A. Kahng, Anne-Sarah Nichitiu, Lucas Cheadle

This study shows OPCs engulf synaptic inputs in a microglia-dependent manner during experience-dependent plasticity in the mouse visual cortex.

bioRxiv · Feb 10, 2022 · PreprintNeuroscience

Microglia and Fn14 regulate transcription and chromatin accessibility in developing neurons

Austin Ferro, Uma Vrudhula, Yohan S. S. Auguste, Lucas Cheadle

This study shows that Fn14 and microglia influence transcription and chromatin accessibility in developing neurons, affecting synaptic function and neural circuit refinement.

bioRxiv · Aug 16, 2021 · PreprintNeuroscience