Author

Uthra Balaji

Weill Cornell Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Jinghua Gu· 2 shared Agnieszka Katarzyna WitkiewicziD· 1 shared Alper EroğluiD· 1 shared Asa ThibodeauiD· 1 shared Asunción MejíasiD· 1 shared Brian K. MannakeeiD· 1 shared Chris P. VerschooriD· 1 shared Colin C. ConineiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

Jinghua Gu

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Single-cell map of the healthy human immune system across the lifespan reveals unique infant immune signatures

Djamel Nehar-Belaid, Asa Thibodeau, Alper Eroğlu, Radu Marcheş, Giray Naim Eryilmaz, Titas Grabauskas, Luke Trinity, Derya Unutmaz, Chris P. Verschoor, Jinghua Gu, Uthra Balaji, Asunción Mejías, Virginia Pascual, George A. Kuchel, Octavio Ramilo, , Duygu Ucar

The paper maps the human immune system across the lifespan using scRNA-seq and snATAC-seq, revealing unique infant immune signatures and age-related changes in immune cell populations.

Nature Communications · Jun 15, 2026Peer-reviewedImmunology

Khdc3 Regulates Metabolism Across Generations in a DNA-Independent Manner

Liana Senaldi, Nora Ali Hassan, Sean M. Cullen, Uthra Balaji, Natalie A. Trigg, Jinghua Gu, Hailey Finkelstein, Kathryn L. Phillips, Colin C. Conine, Matthew Smith-Raska

The paper shows that a mutation in Khdc3 in ancestral mice leads to transgenerational metabolic defects in offspring through epigenetic changes in gametes.

bioRxiv · Feb 27, 2024 · PreprintGenetics

Sensitive and specific post-call filtering of genetic variants in xenograft and primary tumors

Brian K. Mannakee, Uthra Balaji, Agnieszka Katarzyna Witkiewicz, Ryan N. Gutenkunst, Erik S. Knudsen

The paper introduces MAPEX, a BLAST-based algorithm to filter spurious genetic variant calls in xenografts and tumors, achieving comparable sensitivity and specificity to complex methods.

Bioinformatics · Jan 5, 2018Peer-reviewedBioinformatics