Author

V. Alvarez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Alabert· 2 shared A. A. Vorobieva· 1 shared A. Carneiro-Figueira· 1 shared A. Guitian-Caamano· 1 shared A. K. Bera· 1 shared A. Kang· 1 shared A. LEAL-NEGREDO· 1 shared A. Pillai· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

C. Alabert

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cx43 Enhances Response to BRAF/MEK Inhibitors by Reducing DNA Repair Capacity

A. Varela-Vazquez, A. Guitian-Caamano, P. Carpintero-Fernandez, V. Alvarez, A. Carneiro-Figueira, M. Varela-Eirin, T. Calleja-Chucla, S. Bravo, A. Vidal, J. Sendon-Lago, M. Rodriguez-Candela Mateos, J. R. Caeiro, M. G. Blanco, G. Sabio, C. Rivas, , M. D. Mayan

This study shows that Cx43 enhances the effectiveness of BRAF/MEKi by reducing DNA repair, leading to increased DNA damage and cellular senescence, and proposes a novel therapeutic approach using sEVs.

bioRxiv · Jul 15, 2024Cancer Biology

De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles

L. An, M. Said, L. Tran, S. Majumder, I. Goreshnik, G. R. Lee, D. Juergens, J. Dauparas, I. Anishchenko, B. Coventry, A. K. Bera, A. Kang, P. M. Levine, V. Alvarez, A. Pillai, , D. Baker

The paper designs nanomolar binders for diverse small molecules using a pseudocycle-based shape complementarity method, enabling direct conversion into sensing systems.

bioRxiv · Dec 20, 2023 · PreprintBiochemistry

DONSON is required for CMG helicase assembly in the mammalian cell cycle

K. Labib, C. Evrin, V. Alvarez, J. Ainsworth, R. Fujisawa, C. Alabert

This study identifies DONSON as essential for CDC45-MCM-GINS helicase assembly during S-phase, linking it to Meier-Gorlin Syndrome.

bioRxiv · Aug 16, 2023Biochemistry

Interferon-gamma and TNF-alpha synergistically enhance the immunomodulatory capacity of Endometrial-Derived Mesenchymal Stromal Cell secretomes by differential microRNA and extracellular vesicle release

M. d. l. A. de Pedro, F. Marinaro, E. Lopez, M. Pulido, F. M. Sanchez Margallo, V. Alvarez, J. G Casado

This study shows that IFN-gamma and TNF-alpha priming enhances endMSCs' immunomodulatory capacity through increased IDO1 release, altered surface markers, and miRNA secretion.

bioRxiv · Jun 10, 2021Cell Biology

Capillary Electrophoresis of PCR fragments with labelled primers for testing the SARS-Cov-2

J. GOMEZ, S. MELON, J. A. BOGA, M. E. Alvarez-Arguelles, S. ROJO-ALBA, A. LEAL-NEGREDO, C. Castello-Abietar, V. ALVAREZ, E. CUESTA-LLAVONA, E. COTO

The paper develops a capillary electrophoresis-based PCR method for SARS-CoV-2 detection, showing it can identify positive samples and avoid false positives in negative samples.

bioRxiv · May 16, 2020Microbiology