J. Gomez

Diet modulates metabolic and hepatic responses to chronic pesticide mixture exposure in mice

This study shows that dietary context affects the metabolic effects of pesticide mixtures in mice, exacerbating glucose intolerance and insulin resistance on a western diet.

DCLK1-Mediated Regulation of Invadopodia Dynamics and Matrix Metalloproteinase Trafficking Drives Invasive Progression in Head and Neck Squamous Cell Carcinoma

This study identifies DCLK1's role in regulating invadopodia dynamics and MMP trafficking in HNSCC, showing its impact on invasion and metastasis.

Human mobility and malaria risk in peri-urban and rural communities in the Peruvian Amazon

This paper examines how human mobility contributes to malaria transmission in the Peruvian Amazon by analyzing social network patterns and travel behavior.

Staphylococcus aureus Breast Implant Infection Isolates Display Recalcitrance to Antibiotic Pocket Irrigants

This study evaluates the effectiveness of a triple antibiotic pocket irrigant (TAPI) against Staphylococcus aureus in breast implant infections, finding that while TAPI reduces infection in some strains, it promotes biofilm formation in others.

Long-term ovarian cancer survivors: spatial transcriptomics depict ligand-receptor crosstalk heterogeneity at the tumor-stroma interface

SARS-CoV-2 Point Mutation and Deletion Spectra, and Their Association with Different Disease Outcome

The paper analyzes SARS-CoV-2 mutant spectra from diagnostic samples and finds higher point mutation complexity in isolates from patients with mild disease compared to moderate or severe disease.

Studies of Salt and Stress Sensitivity on Arterial Pressure in Renin-b Deficient Mice

This study investigates the effect of renin-b deficiency on salt and stress-induced blood pressure changes in mice, finding no exaggerated pressor response to high salt but a trend for myocardial enlargement and no difference in stress response.

Amino acid substitutions associated with treatment failure of hepatitis C virus infection

The paper identifies six amino acid substitutions associated with HCV treatment failure that are not resistance-associated substitutions but are highly represented in viral quasispecies.

Dissimilar conservation pattern in hepatitis C virus mutant spectra, consensus sequences, and data banks

The paper examines conservation patterns in HCV mutant spectra, consensus sequences, and data banks, finding mismatches that challenge assumptions about sequence conservation for vaccine design.

Capillary Electrophoresis of PCR fragments with labelled primers for testing the SARS-Cov-2

The paper develops a capillary electrophoresis-based PCR method for SARS-CoV-2 detection, showing it can identify positive samples and avoid false positives in negative samples.

Large-scale chemical-genetics yields new Mycobacterium tuberculosis inhibitor classes

This study uses a novel chemical-genetics screening strategy to identify new inhibitors of Mycobacterium tuberculosis, revealing novel compound classes targeting previously unexplored bacterial targets.