Nuclear myosin VI maintains replication fork stability
J. Shi, K. Hauschulte, I. Mikicic, S. Maharjan, V. Arz, J. B. Heidelberger, J. V. Schaefer, B. Dreier, A. Plueckthun, P. Beli, H. D. Ulrich, H.-P. Wollscheid
This study shows that nuclear myosin VI stabilizes stalled or reversed replication forks by interacting with WRNIP1 to prevent DNA2-mediated degradation during replication stress.
bioRxiv · Jul 28, 2022Cell Biology