A tyrosine kinase protein interaction map reveals targetable EGFR network oncogenesis in lung cancer
S. Kaushik, F. Haderk, X. Zhao, H.-M. Hu, K. N. Shah, G. M. Jang, V. Olivas, S. Nanjo, V. B. Masto, D. Ciznadija, I. Sloma, E. Gross, S. L. Weinrich, J. R. Johnson, T. G. Bivona, , S. Bandyopadhyay
The paper constructs a tyrosine kinase protein interaction map, revealing EGFR network oncogenesis in 19% of EGFR wild-type lung cancers, which is targetable with EGFR inhibitors.
bioRxiv · Jul 2, 2020 · PreprintCancer Biology