Author

V. Bernal-Crespo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

J. Wang· 2 shared S. Matosevic· 2 shared S. Utturkar· 2 shared A. L. Sinn· 1 shared A. M. Chambers· 1 shared B. D. Elzey· 1 shared B. Elzey· 1 shared G. T. Knipp· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

J. Wang

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2 papers

Recent·Most cited

Engineered natural killer cells impede the immunometabolic CD73-adenosine axis in solid tumors

A. M. Chambers, K. B. Lupo, J. Wang, J. Cao, S. Toregrosa-Allen, B. Elzey, S. Pine, S. Jalal, S. Utturkar, N. Atallah Lanman, V. Bernal-Crespo, S. Matosevic

This study engineers natural killer cells to block the CD73-adenosine axis in solid tumors, leading to tumor cell killing and enhanced NK cell activity.

bioRxiv · Oct 5, 2021Immunology

Tumor-responsive, multifunctional CAR-NK cells cooperate with impaired autophagy to infiltrate and target glioblastoma

J. Wang, S. Torregrosa-Allen, B. D. Elzey, S. Utturkar, N. A. Lanman, V. Bernal-Crespo, M. M. Behymer, G. T. Knipp, Y. Yun, M. C. Veronesi, A. L. Sinn, K. E. Pollok, R. R. Brutkiewicz, K. S. Nevel, S. Matosevic

This study develops multifunctional CAR-NK cells that target glioblastoma by addressing antigen escape, poor immune cell homing, and immunometabolic suppression through tumor-specific antibody fragments and autophagy inhibition.

bioRxiv · Oct 7, 2020 · PreprintImmunology