Author

Y. Yun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2 Biophysics· 1 Ecology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 5 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:Bayesian inference· 1

Frequent Co-Authors

K. E. Pollok· 2 shared M. C. Veronesi· 2 shared S. Lee· 2 shared X. Chen· 2 shared A. A. Shibl· 1 shared A. E. Vaughan· 1 shared A. Inoue· 1 shared A. Isaac· 1 shared

Activity by Year

2017-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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2 shared papersCell Biology

K. E. Pollok

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Author profile →

10 papers

Recent·Most cited

Golgi-associated retrograde protein (GARP) complex recruits retromer to trans-Golgi network for FgKex2 and FgSnc1 recycling, necessary for development and pathogenicity of Fusarium graminearum

Y. Long, X. Chen, J. Chen, H. Zhang, Y. Lin, S. Cheng, N. Pu, X. Zhou, R. Sheng, Y. S. Abubakar, H. Zheng, Y. Yun, G. Lu, Z. Wang, W. Zheng

This study identifies the GARP complex as a mediator that recruits retromer to the trans-Golgi network, facilitating the recycling of FgKex2 and FgSnc1, which is essential for growth, development, and pathogenicity of Fusarium graminearum.

New Phytologist · Feb 15, 2025Peer-reviewedMicrobiology

An injury-induced tissue niche shaped by mesenchymal plasticity coordinates the regenerative and disease response in the lung

D. L. Jones, M. P. Morley, X. Li, Y. Yun, F. L. Cardenas-Diaz, S. Li, S. Zhou, S. E. Schaefer, U. V. Chembazhi, A. Nottingham, S. Lin, E. Cantu, J. M. Diamond, M. C. Basil, A. E. Vaughan, E. E. Morrisey

The paper identifies an injury-induced tissue niche (iTCH) in the lung that coordinates regenerative and disease responses through mesenchymal plasticity and signaling pathways.

bioRxiv · Feb 26, 2024 · PreprintCell Biology

Reduced oocyte quality and exacerbation of the maternal age effect are enduring consequences of low-level atrazine exposure in mouse

Y. Yun, S. Lee, C. So, R. Manhas, C. Kim, T. Wibowo, M. Hori, N. Hunter

This study shows that low-level atrazine exposure in mice impairs oocyte quality and worsens age-related aneuploidy, with effects lasting long after exposure ends.

bioRxiv · Aug 23, 2022 · PreprintPharmacology & Toxicology

ECPAS/Ecm29-Mediated 26S Proteasome Disassembly Is an Adaptive Response to Glucose Starvation

W. H. Choi, Y. Yun, I. Byun, S. Lee, J. Sim, S. Levi, S. Kim, S. H. Park, J. Jun, K. P. Kim, Y. T. Kwon, D. Han, T. Chiba, C. Seok, M. H. Glickman, M. J. Lee

This study shows that ECPAS-mediated 26S proteasome disassembly into 20S and 19S subcomplexes occurs during glucose starvation, enhancing proteolysis and cell survival.

bioRxiv · Jun 6, 2022Biochemistry

Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

P. Sarma, H.-J. Yoon, C. M. Carino, D. S., R. Banerjee, Y. Yun, J. Ji, K. Min, S. Pandey, H. Dwivedi-Agnihotri, X. Rui, Y. Cao, K. Kawakami, Y.-C. Chen, P. Kumari, , A. K. Shukla

This study characterizes the biased agonism of CXCR4 and CXCR7, revealing differences in G-protein coupling, β-arrestin recruitment, and ERK1/2 activation.

bioRxiv · Jun 6, 2022Biochemistry

Molecular mechanisms of microbiome modulation by the eukaryotic secondary metabolite azelaic acid

A. A. Shibl, M. A. Ochsenkuhn, A. R. Mohamed, A. Isaac, L. S. Y. Coe, Y. Yun, G. Skrzypek, J.-B. Raina, J. R. Seymour, A. J. Afzal, S. A. Amin

This study investigates how azelaic acid affects two microalgal-associated bacteria, identifying uptake mechanisms and toxicity pathways, and shows its role in shaping microbial communities in marine environments.

bioRxiv · Apr 8, 2022Ecology

Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor

Y. Wang, S. Guo, Y. Zhuang, Y. Yun, P. Xu, X. He, J. Guo, W. Yin, H. E. Xu, X. Xie, Y. Jiang

The paper presents cryo-EM structures of the ghrelin receptor bound to ghrelin and GHRP-6, revealing the binding pocket for the octanoyl group and providing insights for drug design.

bioRxiv · Jun 9, 2021Biophysics

Development of Targetable Multi-Drug Nanoparticles for Glioblastoma Treatment and In Vitro Evaluation in Glioblastoma Stem Cells

S. B. Smiley, Y. Yun, P. Ayyagari, H. E. Shannon, K. E. Pollok, M. W. Vannier, S. K. Das, M. C. Veronesi

This paper develops multi-drug nanoparticles targeting GBM stem cells and evaluates their in vitro efficacy against these cells.

bioRxiv · Nov 8, 2020 · PreprintCell Biology

Tumor-responsive, multifunctional CAR-NK cells cooperate with impaired autophagy to infiltrate and target glioblastoma

J. Wang, S. Torregrosa-Allen, B. D. Elzey, S. Utturkar, N. A. Lanman, V. Bernal-Crespo, M. M. Behymer, G. T. Knipp, Y. Yun, M. C. Veronesi, A. L. Sinn, K. E. Pollok, R. R. Brutkiewicz, K. S. Nevel, S. Matosevic

This study develops multifunctional CAR-NK cells that target glioblastoma by addressing antigen escape, poor immune cell homing, and immunometabolic suppression through tumor-specific antibody fragments and autophagy inhibition.

bioRxiv · Oct 7, 2020 · PreprintImmunology

Inferring Phylogenetic Networks Using PhyloNet

D. Wen, Y. Yun, J. Zhu, L. Nakhleh

The paper describes the evolution and features of PhyloNet, a software package for inferring phylogenetic networks from genetic data.

bioRxiv · Dec 22, 2017Evolutionary Biology