v. Chaptal

R6G narrows BmrA conformational spectrum for a more efficient use of ATP

This study shows that Rhodamine6G binding to BmrA narrows its conformational spectrum, enhancing ATP-dependent transport efficiency.

X-Ray Structure and enzymatic study of a Bacterial NADPHoxidase highlight the activation mechanism of eukaryoticNOX

The paper presents crystal structures of SpNOX and its DH domain, revealing the activation mechanism of eukaryotic NOX by elucidating hydride transfer and flavin binding.

Conformational space exploration of cryo-EM structures by variability refinement

This paper introduces a tool to refine ensembles of structures into maps from cryo-EM variability analysis, enabling identification of variable and static structural elements.

Collinearity of alpha-helices or beta strands in membrane proteins causes a characteristic peak centred on 4.9 A resolution in diffraction intensity profiles, inducing higher diffraction anisotropy

Drug-bound and -free outward-facing structures of a multidrug ABC exporter point to a swing mechanism

The paper resolves two ATP-Mg2+-bound outward-facing conformations of BmrA, revealing a swing mechanism for drug transport through structural and dynamic analyses.

Nanodisc, amphipol or detergent belts in cryoEM reconstructions of membrane proteins are similar and correspond to a common ordered solvent layer

The paper compares belt structures in cryo-EM reconstructions of membrane proteins solved in nanodiscs, amphipols, or detergents, finding they are similar and represent a common ordered solvent layer.