Author

V. Chennathukuzhi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Majumbar· 1 shared A. Yang· 1 shared D. A. Harki· 1 shared D. Rasmussen· 1 shared E. B. Faber· 1 shared E. Roberts· 1 shared E. Schonbrunn· 1 shared F. Qiu· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Majumbar

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2 papers

Recent·Most cited

Characterization of m6A modifiers and RNA modifications in uterine fibroids

J. W. George, R. Cancino, J. L. G. Miller, F. Qiu, Q. Lin, J. Rowley, V. Chennathukuzhi, J. S. Davis

This study characterizes m6A modifiers and RNA modifications in uterine fibroids using RNA-seq, RT-qPCR, and mass spectrometry, finding limited differential expression despite heterogeneity.

bioRxiv · Aug 7, 2023Cancer Biology

Development of allosteric, selective cyclin-dependent kinase 2 (CDK2) inhibitors that are negatively cooperative with cyclin binding and show potential as contraceptive agents

E. B. Faber, J. Tang, E. Roberts, S. Ganeshkumar, L. Sun, N. Wang, D. Rasmussen, A. Majumbar, K. John, A. Yang, H. Khalid, J. E. Hawkinson, N. M. Levinson, E. Schonbrunn, V. Chennathukuzhi, , G. I. Georg

This paper develops high-affinity, structurally confirmed allosteric CDK2 inhibitors that show negative cooperativity with cyclin binding and demonstrate contraceptive potential in mouse testicular explants.

bioRxiv · Jun 30, 2022 · PreprintPharmacology & Toxicology