Author

V. de Lorenzo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7 Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Organism:bacteria (other)· 8 Assay:metabolomics· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

P. Dvorak· 3 shared A. Nyerges· 2 shared A. Sanchez-Pascuala· 2 shared B. Calles· 2 shared E. Martinez-Garcia· 2 shared P. I. Nikel· 2 shared T. Aparicio· 2 shared A. Goni-Moreno· 1 shared

Activity by Year

2018-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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3 shared papersBioengineering

P. Dvorak

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Genomic and metabolic plasticity drive alternative scenarios for adapting Pseudomonas putida to non-native substrate D-xylose.

P. Dvorak, B. Buryskova, B. Popelarova, B. E. Ebert, T. Botka, D. Bujdos, A. Sanchez-Pascuala, H. Schoettler, H. Hayen, V. de Lorenzo, L. M. Blank, M. Benesik

This study investigates how Pseudomonas putida adapts to xylose by combining metabolic engineering and adaptive evolution, revealing genomic and metabolic plasticity that enables growth on the non-native sugar.

bioRxiv · May 19, 2023 · PreprintBioengineering

An updated structural model of the A domain of the Pseudomonas putida XylR regulator exposes a distinct interplay with aromatic effectors

P. Dvorak, C. Alvarez-Carreno, S. Ciordia, A. Paradela, V. de Lorenzo

The paper presents an updated structural model of the XylR A domain in Pseudomonas putida, revealing how aromatic effectors influence its folding and activation rather than binding dynamically to a pre-formed structure.

bioRxiv · Jan 17, 2021Microbiology

Redox stress reshapes carbon fluxes of Pseudomonas putida for cytosolic glucose oxidation and NADPH generation

P. I. Nikel, T. Fuhrer, M. Chavarria, A. Sanchez-Pascuala, U. Sauer, V. de Lorenzo

This study investigates how oxidative stress in Pseudomonas putida reconfigures carbon fluxes to enhance NADPH production and support redox stress responses.

The ISME Journal · Jan 11, 2021Peer-reviewedMicrobiology

The subcellular architecture of the xyl gene expression flow of the TOL catabolic plasmid of Pseudomonas putida mt-2

J. Kim, A. Goni-Moreno, V. de Lorenzo

This paper investigates the subcellular localization and spatial dynamics of xyl mRNAs in Pseudomonas putida mt-2, revealing they cluster away from the nucleoid and ribosomes, suggesting decoupled transcription and translation.

bioRxiv · Aug 30, 2020Microbiology

The Wsp intermembrane complex mediates metabolic control of the swim-attach decision of Pseudomonas putida

M. A. Hueso, B. Calles, V. de Lorenzo

This study investigates the wsp operon in Pseudomonas putida, showing it mediates metabolic control of the swim-attach decision through WspR and WspF, with functional similarities to Pseudomonas aeruginosa.

bioRxiv · Feb 5, 2020Microbiology

In vivo diversification of target genomic sites using processive T7 RNA polymerase-base deaminase fusions blocked by RNA-guided dCas9

B. Alvarez, M. Mencia, V. de Lorenzo, L. A. Fernandez

This paper develops an in vivo system to diversify specific DNA segments using T7 RNA polymerase-base deaminase fusions blocked by RNA-guided dCas9, demonstrating efficiency in E. coli.

bioRxiv · Nov 22, 2019 · PreprintBioengineering

High-efficiency multi-site genomic editing (HEMSE) of Pseudomonas putida through thermoinducible ssDNA recombineering

T. Aparicio, A. Nyerges, E. Martinez-Garcia, V. de Lorenzo

This paper develops a method for efficient genomic editing in Pseudomonas putida using thermoinducible ssDNA recombineering to overcome MMR limitations.

bioRxiv · Nov 21, 2019Microbiology

Biotransformation of D-xylose to D-xylonic acid coupled to medium chain length polyhydroxyalkanoate production in cellobiose-grown Pseudomonas putida EM42.

P. Dvorak, J. Kovac, V. de Lorenzo

This study demonstrates Pseudomonas putida EM42's ability to co-produce D-xylonic acid and medium chain length polyhydroxyalkanoates from D-xylose and D-cellobiose.

bioRxiv · Nov 10, 2019 · PreprintBioengineering

Mismatch repair hierarchy of Pseudomonas putida revealed by mutagenic ssDNA recombineering of the pyrF gene

V. de Lorenzo, E. Martinez-Garcia, I. Nagy, C. Pal, A. Nyerges, T. Aparicio

The paper investigates the mismatch repair hierarchy in Pseudomonas putida using mutagenic ssDNA recombineering of the pyrF gene, revealing a specific order of mismatch recognition.

bioRxiv · Jul 22, 2019Microbiology

The metabolic redox regime of Pseudomonas putida tunes its evolvability towards novel xenobiotic substrates

O. Akkaya, D. Perez-Pantoja, B. Calles, P. I. Nikel, V. de Lorenzo

This paper shows that the redox state of Pseudomonas putida influences its ability to evolve new metabolic pathways for degrading 2,4-DNT by modulating oxidative stress and mutagenesis.

bioRxiv · May 4, 2018Microbiology