J. Loncarek

EWSR1's visual modalities are defined by its association with nucleic acids and RNA polymerase II

This study identifies two visual modalities of EWSR1 in the nucleoplasm, both associated with nascent RNA, and shows EWSR1 foci localize to euchromatin and phosphorylated RNA polymerase II.

Procentriole microtubules as drivers of centriole reduplication

The paper investigates how procentriole microtubules drive centriole reduplication, showing that their structural changes lead to centriole disengagement and reduplication during cell cycle arrests.

Regulation of Cilia Abundance in Multiciliated Cells

This study shows that centriole and cilia abundance in multiciliated cells is controlled by surface area, not parental centrioles or Plk4.

PLK4 is a microtubule-associated protein that self assembles promoting de novo MTOC formation

The paper shows PLK4 self-assembles into structures that recruit tubulin and form de novo MTOCs in Xenopus extracts.

Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells

This study shows that delta-tubulin and epsilon-tubulin are essential for stable centriole formation and inheritance in human cells by maintaining triplet microtubules.