Author

V. J. Morley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. F. Read· 3 shared D. G. SIm· 2 shared R. J. Woods· 2 shared A. Penkevich· 1 shared A. Sheikhi· 1 shared C. Bator· 1 shared C. L. Kinnear· 1 shared E. Hansen· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBioengineering

A. F. Read

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Author profile →

3 papers

Recent·Most cited

Ion exchange biomaterials to capture daptomycin and prevent resistance evolution in off-target bacterial populations

S.-L. Yeh, N. Narasimhalu, L. G. vom Steeg, J. Muthami, S. LeConey, Z. He, M. Pitcher, H. Cassady, V. J. Morley, S. H. Cho, C. Bator, R. Koshani, R. J. Woods, M. Hickner, A. F. Read, A. Sheikhi

This study shows ion exchange biomaterials can capture daptomycin in the gut, preventing resistance evolution in off-target bacteria.

bioRxiv · Jun 10, 2022Bioengineering

Oral cholestyramine prevents enrichment of diverse daptomycin-resistance mutations in intestinal Enterococcus faecium

V. J. Morley, D. G. SIm, A. Penkevich, R. Woods, A. F. Read

This study shows that cholestyramine prevents the enrichment of daptomycin-resistant Enterococcus faecium mutations in the gut when administered before or after daptomycin treatment.

bioRxiv · May 25, 2022 · PreprintMicrobiology

An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

V. J. Morley, C. L. Kinnear, D. G. Sim, S. N. Olson, L. M. Jackson, E. Hansen, G. A. Usher, S. A. Showalter, M. P. Pai, R. J. Woods, A. F. Read

This study shows that cholestyramine, when used with daptomycin, reduces the spread of antibiotic-resistant Enterococcus faecium in mice.

bioRxiv · Apr 24, 2020Evolutionary Biology