Author

D. G. SIm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Ecology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

A. F. Read· 4 shared M. J. Jones· 2 shared V. J. Morley· 2 shared A. A. King· 1 shared A. Penkevich· 1 shared C. J. Field· 1 shared C. L. Kinnear· 1 shared D. R. Patel· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersMicrobiology

A. F. Read

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Divergent Evolutionary Pathways of Myxoma Virus in Australia: Virulence Phenotypes in Susceptible and Partially Resistant Rabbits Indicate Possible Selection for Transmissibility

P. J. Kerr, I. M. Cattadori, D. G. SIm, J. Liu, E. C. Holmes, A. F. Read

This study examines the evolution of myxoma virus in Australian rabbits through experimental infections, revealing diverse virulence phenotypes and suggesting selection for transmissibility over inflammation.

bioRxiv · Jun 2, 2022Microbiology

Oral cholestyramine prevents enrichment of diverse daptomycin-resistance mutations in intestinal Enterococcus faecium

V. J. Morley, D. G. SIm, A. Penkevich, R. Woods, A. F. Read

This study shows that cholestyramine prevents the enrichment of daptomycin-resistant Enterococcus faecium mutations in the gut when administered before or after daptomycin treatment.

bioRxiv · May 25, 2022 · PreprintMicrobiology

Transmission and protection against re-infection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate

D. R. Patel, C. J. Field, K. M. Septer, D. G. SIm, M. J. Jones, T. A. Heinly, E. A. McGraw, T. C. Sutton

This study evaluates transmission modes and immunity duration against SARS-CoV-2 in ferrets, finding direct contact transmission is efficient and immunity lasts at least 56 days, but intramuscular vaccination does not prevent upper respiratory tract infection.

bioRxiv · Nov 20, 2020Microbiology

An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

V. J. Morley, C. L. Kinnear, D. G. Sim, S. N. Olson, L. M. Jackson, E. Hansen, G. A. Usher, S. A. Showalter, M. P. Pai, R. J. Woods, A. F. Read

This study shows that cholestyramine, when used with daptomycin, reduces the spread of antibiotic-resistant Enterococcus faecium in mice.

bioRxiv · Apr 24, 2020Evolutionary Biology

Breaking down defenses: Quantitative analysis of malaria infection dynamics reveals distinct immune defense strategies

N. Wale, M. J. Jones, D. G. Sim, A. F. Read, A. A. King

This study quantifies immune defense strategies against malaria by analyzing parasite and RBC dynamics, revealing coordinated resource-directed strategies that benefit the host.

bioRxiv · Aug 17, 2019 · PreprintEcology