Author

V. L. Gillespie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Garcia-Sastre· 1 shared A. T. Ting· 1 shared F. Amanat· 1 shared F. Krammer· 1 shared H. Xiong· 1 shared J. P. Sundberg· 1 shared L. Coughlan· 1 shared M. B. Uccellini· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Garcia-Sastre

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2 papers

Recent·Most cited

Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death

R. L. Ang, J. P. Sundberg, S.-C. Sun, V. L. Gillespie, P. Heeger, H. Xiong, S. A. Lira, A. T. Ting

This study shows that immune dysregulation in SHARPIN-deficient mice depends on CYLD-mediated cell death, with CYLD inhibition leading to TNF-induced cell death and multi-organ inflammation.

bioRxiv · Jan 27, 2020Immunology

Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection

R. Rathnasinghe, S. Strohmeier, F. Amanat, V. L. Gillespie, F. Krammer, A. Garcia-Sastre, M. Schotsaert, L. Coughlan, M. B. Uccellini

This study compares two SARS-CoV-2 infection models in mice: K18-hACE2 transgenic and adenovirus-mediated hACE2 delivery, showing differences in viral replication and disease outcomes.

Emerging Microbes & Infections · Jan 1, 2020Peer-reviewedMicrobiology