A major Role for Nrf2 transcription factors in cell transformation by KSHV encoded oncogenes.
D. Sapochnik, A. Raimondi, V. Medina, J. Naipauer, E. Mesri, O. Coso
This study identifies Nrf2 transcription factors as key mediators of KSHV oncogene-induced cell transformation through the vGPCR-Ga13-RhoA signaling pathway and Erk1/2 MAPK activation.
bioRxiv · Jun 21, 2019 · PreprintCancer Biology