Author

J. A. Coleman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Ciacci· 1 shared A. Sau· 1 shared B. Thomas· 1 shared D. Antermite· 1 shared D. J. Hickey· 1 shared D. Yang· 1 shared E. Gouaux· 1 shared F. S. Ng· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPhysiology

A. Ciacci

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural mechanisms for VMAT2 inhibition by tetrabenazine

M. P. Dalton, M. H. Cheng, I. Bahar, J. A. Coleman

This study reports the cryo-EM structure of VMAT2 bound to tetrabenazine, revealing its inhibition mechanism and conformational dynamics.

bioRxiv · Sep 5, 2023 · PreprintBiochemistry

Identifying locations susceptible to micro-anatomical reentry using a spatial network representation of atrial fibre maps

M. Falkenberg, J. A. Coleman, S. Dobson, D. J. Hickey, L. Terrill, A. Ciacci, B. Thomas, N. S. Peters, A. Sau, F. S. Ng, J. Zhao, K. Christensen

This paper introduces a computational method to identify atrial regions susceptible to micro-reentry by modeling percolation-like phenomena on spatial networks of atrial fibre maps.

PLOS ONE · Jun 23, 2022Peer-reviewedPhysiology

Chemical and structural investigation of the paroxetine-human serotonin transporter complex

J. A. Coleman, V. Navratna, D. Antermite, D. Yang, J. A. Bull, E. Gouaux

The paper investigates the binding of paroxetine and its analogs to the serotonin transporter using structural and biochemical methods, revealing how they stabilize the outward-open conformation and inhibit serotonin transport.

bioRxiv · Feb 26, 2020Biochemistry