Dynamic structural order of a low complexity domain facilitates assembly of intermediate filaments
V. O. Sysoev, M. Kato, L. Sutherland, R. Hu, S. L. McKnight, D. T. Murray
The paper shows that low complexity domains in Drosophila Tm1 proteins form labile cross-β interactions, facilitating intermediate filament assembly through dynamic structural transitions.
bioRxiv · Apr 1, 2020Biochemistry