Author

V. Pelicic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:bacteria (other)· 6 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Assay:structural biology· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Assay:cryo-EM· 1

Frequent Co-Authors

I. Gurung· 4 shared J.-L. Berry· 4 shared C. Raynaud· 3 shared D. Sheppard· 3 shared L. Pieulle· 2 shared M. Shahin· 2 shared O. Valette· 2 shared S. Matthews· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersMicrobiology

I. Gurung

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Author profile →

8 papers

Recent·Most cited

A Toolbox for Neisseria meningitidis: Gene Editing, Complementation and Labelling

M. Wuckelt, A. Laurent, C. Mouville, J. Meyer, A. Jamet, H. Lecuyer, X. Nassif, E. Bille, V. Pelicic, M. Coureuil

This study introduces new tools for markerless mutation, genetic complementation, and labelling in Neisseria meningitidis to enhance research on these pathogens.

bioRxiv · Mar 14, 2024Microbiology

Systematic functional analysis of the Com pilus in Streptococcus sanguinis: a minimalistic type 4 filament dedicated to DNA uptake in monoderm bacteria

J. Mom, I. Chouikha, O. Valette, L. Pieulle, V. Pelicic

This study systematically analyzes the Com pilus in Streptococcus sanguinis, showing it is a minimalistic type 4 filament essential for DNA uptake during natural transformation.

bioRxiv · Sep 19, 2023Microbiology

Structure of a heteropolymeric type 4 pilus from a monoderm bacterium

R. Anger, L. Pieulle, M. Shahin, O. Valette, H. Le Guenno, A. Kosta, V. Pelicic, R. Fronzes

The paper determines the structure of a heteropolymeric type 4 pilus from a monoderm bacterium, revealing conserved features of bacterial type 4 filaments.

bioRxiv · Jun 15, 2023Microbiology

Full structure/function analysis of all the pilin subunits in a type 4 pilus: a complex of minor pilins in Streptococcus sanguinis mediates binding to glycans

M. Shahin, D. Sheppard, C. Raynaud, J.-L. Berry, I. Gurung, L. M. SIlva, T. Feizi, Y. Liu, V. Pelicic

The paper determines the structures and functions of minor pilins in Streptococcus sanguinis T4P, showing they form a tip complex that mediates adhesion to host glycans.

bioRxiv · Aug 25, 2022Microbiology

PilB from Streptococcus sanguinis is a bimodular type IV pilin with a direct role in adhesion

C. Raynaud, D. Sheppard, J.-L. Berry, I. Gurung, V. Pelicic

This study identifies PilB from Streptococcus sanguinis as a bimodular type IV pilin with a metal-binding vWA domain that enhances adhesion and twitching motility.

bioRxiv · Jan 27, 2021Microbiology

Construction of a complete set of Neisseria meningitidis defined mutants - the NeMeSys 2.0 collection - and its use for the phenotypic profiling of the genome of an important human pathogen

A. Muir, I. Gurung, A. Cehovin, A. Bazin, D. Vallenet, V. Pelicic

The paper constructs a comprehensive mutant collection for Neisseria meningitidis and identifies essential genes and novel gene functions related to key biological processes.

bioRxiv · Aug 12, 2020Microbiology

The major subunit of widespread competence pili exhibits a novel and conserved type IV pilin fold

D. Sheppard, J.-L. Berry, R. Denise, E. P. Rocha, S. Matthews, V. Pelicic

The paper reports the structural and phylogenetic analysis of ComGC, a major pilin subunit of competence pili, revealing a novel and conserved type IV pilin fold across multiple bacterial species.

Journal of Biological Chemistry · May 1, 2020Peer-reviewedMicrobiology

Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium Streptococcus sanguinis

J.-L. Berry, I. Gurung, J. H. Anonsen, I. Spielman, E. Harper, A. M. J. Hall, V. J. Goosens, C. Raynaud, M. Koomey, N. Biais, S. Matthews, V. Pelicic

This study presents the first global biochemical and structural analysis of type IV pili in a Gram-positive bacterium, revealing unique features of pilin processing, structure, and function.

bioRxiv · Mar 1, 2019Microbiology